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Embarrassing: Niners 3, Eagles 42

Alex Smith, the top pick in the NFL draft, made his debut for San Francisco, playing the last series.

Six days after losing to Atlanta 14-10 in a rematch of last season's NFC championship game, the Eagles dominated the 49ers (1-1) from the start.

McNabb and Owens connected for a 68-yard TD on the third play from scrimmage, electrifying a sellout crowd at Lincoln Financial Field that hadn't seen a meaningful game since the Eagles advanced to the Super Bowl.

McNabb, who missed practice Wednesday because of a bruised chest, eluded a strong rush, scrambled to his left, and threw on the run, hitting Owens in stride at San Francisco's 41. The star wideout outran cornerback Mike Adams to the end zone, turned around and raced straight toward McNabb. The two stars, who feuded throughout the summer, low-fived each other and went to the sideline smiling.